In 2006, the environmental engineering program study under civil engineering was established as a response by faculty of engineering Universitas Indonesia for the needs of engineer in the field of environmental and biology. Later, the education in this field is strengthen by the establishment of bioprocess engineering undergraduate program in 2007.
In 2016, as an impact of growing interest in research in the field of biomedical and bioengineering, faculty of engineering establish Research Centre for Biomedical Engineering (RCBE) that focus solely on research in the field of biomedical.
As a growing research focus on biomedical continues in faculty of engineering, in 2017, master program of biomedical engineering is relocated from medicine faculty to engineering faculty to support the research and education in this area. This trend continues with the development of undergraduate program of biomedical engineering in 2018.
As the needs of education, research, and services in the field of biosystem and bioengineering continues to arises in recent years, The Institute of Biosystem and Bioengineering (IBB) is established in 2022 as a hub for interdisciplinary education, research, and services in the field of bioengineering and biosystem.